Endocrine Abstracts

Introduction: Tumors derived from the paraganglionic system are rare. 90% of them are located on the adrenal gland, and the remaining 10% are extra-adrenal. Within this last group, 85% are located in the abdomen, 12% in the thorax, and 3% in the head and neck region (HNPG). Its proximity to important structures represents a great difficulty for resection. This makes it necessary to refer these patients to reference centers with multidisciplinary teams and specific surgical tra...

Introduction: Tumors derived from the extra-adrenal paraganglionic system are rare (incidence: 0.8/100,000 people/year). In this group, 85% are located in the abdomen, 12% in the thorax, and 3% in the head and neck region (HNPC).Case report: A 46-year-old man, ex-smoker, with a personal history of arterial hypertension, multifactorial secondary polycythemia (obesity, OSA syndrome, hypertrophic cardiomyopathy). Family history: one brother with paraganglio...

Introduction: Graves’ orbitopathy (GO) is the most common extrathyroidal manifestation of Graves’ disease. The first-line treatment are intravenous corticoids in active moderate-severe GO. Tocilizumab is a humanized monoclonal antibody against the IL-6 receptor which has been approved for the treatment of rheumatoid arthritis and is in its research stage for patients with corticosteroid-refractory GO.Objectives: To assess the experience with to...